This Slow Cooker Mississippi Pot Roast is the ultimate easy dinner and you only need five ingredients. Chuck roast, ranch mix, au jus gravy mix, butter, and pepperoncini, and the slow cooker does all the work. It’s tender, flavorful, and perfect for a low-effort family meal.

Mississippi Pot Roast By Tessie's Table. — Photo Credit: Tessie’s Table.

This recipe is ideal for busy nights or lazy weekends when you want something hearty without spending much time in the kitchen. It’s rich, savory, and makes enough for leftovers that taste even better the next day. If you enjoy simple slow cooker recipes, try my Slow Cooker Shredded Beef , Slow Cooker Beef Stew or my Slow Cooker Butter Chicken Meatballs next, they are just as easy and versatile.

Why you’ll love this Slow Cooker Mississippi Pot Roast

It’s the easiest dinner ever.
Everything goes straight into the slow cooker, and by the time dinner rolls around, you’ve got the most tender, flavorful roast waiting for you.
The flavor is unreal:
The mix of ranch, au jus, butter, and pepperoncini gives it a rich, savory sauce with just a little tang. It’s buttery, beefy, and hard to stop eating once you start.
You can serve it so many ways.
Pile it on Mashed Potatoes, stuff it into sandwiches, or scoop it over Rice. It’s one of those recipes that never gets boring, and the leftovers are even better.

Close-up of tender Mississippi Pot Roast served on platter with pepperoncini and rustic bread in the background.

Easy Slow Cooker Mississippi Pot Roast for Family Dinners

I started making this pot roast on weekends when I wanted something hearty but easy. It reminds me of the slow-cooked dinners we had growing up in Ireland, but with the big, bold flavor of Southern comfort food I’ve come to love living here in Atlanta.

Ingredients Needed for Slow Cooker Mississippi Pot Roast

Chuck roast: Becomes tender and juicy after hours in the slow cooker.
Ranch dressing mix: Adds tangy, herby flavor that complements the beef.
Au jus gravy mix: Deepens the savory taste and makes a rich sauce.
Butter: Melts into the roast and creates a smooth, flavorful finish.
Pepperoncini Peppers: Give a mild, tangy kick that balances the richness.

Ingredients for Slow Cooker Mississippe Pot Roast By Tessie's Table. (1)

How to make Slow Cooker Mississippi Pot Roast

**For more detailed instructions, please refer to the printable recipe card below.**

Raw chuck roast in a white slow cooker with dry ranch and au jus seasoning sprinkled on top for Slow Cooker Mississippi Pot Roast.

Place the chuck roast in the slow cooker and sprinkle the ranch and au jus mixes evenly over the top.

Chuck roast in slow cooker topped with butter cubes, ranch mix, au jus mix, and whole pepperoncini peppers before cooking Mississippi Pot Roast.

Add the butter and pepperoncini and pepperoncini juice.

Cooked Mississippi Pot Roast in slow cooker with tender beef and pepperoncini peppers in rich brown sauce.

Cover and cook on low for 8 hours or until tender.

Slow-cooked chuck roast resting in slow cooker with wooden utensils lifting tender pieces of Mississippi Pot Roast.

Remove the roast from the slow cooker and set it aside on a plate.

Juicy sauce and cooked pepperoncini peppers left in the slow cooker after removing Mississippi Pot Roast.

Skim any excess fat from the surface of the cooking liquid if needed.

Tender chunks of shredded Mississippi Pot Roast on a white serving dish with two forks ready for pulling apart.

Shred the beef using two forks.

Shredded Slow Cooker Mississippi Pot Roast in white crockpot surrounded by pepperoncini peppers in flavorful gravy.

Return it to the slow cooker and stir to coat it in the sauce

Variations

Mississippi Pot Roast Sandwiches: Shred the beef and pile it high on toasted rolls with melted provolone or mozzarella. It makes an easy dinner or a great way to use up leftovers the next day.
Spicy version: If you like a little heat, add more pepperoncini or pour in some of the brine from the jar. It adds a nice kick without taking away from that buttery flavor.
Mississippi Pot Roast with Gravy: Want it a bit thicker? Stir a small cornstarch slurry into the sauce after cooking. It turns into a rich, glossy gravy that’s perfect for spooning over mashed potatoes.
Oven-baked version: Don’t have a slow cooker? No problem. Layer everything in a Dutch oven, cover tightly, and bake at 300°F for about 3 hours until tender. The flavor comes out just as delicious.
Mississippi Pot Roast Sliders: This one’s fun for parties. Use the shredded beef on slider buns, top with cheese, and bake until everything’s warm and melty. They disappear fast at get-togethers.

Serving Suggestions

Garlic Mashed Potatoes: This pot roast and creamy mashed potatoes are made for each other. My Garlic Mashed Potatoes soak up every bit of that flavorful sauce and make the meal feel complete.
Rustic Bread: A thick slice of Rustic Bread on the side is perfect for mopping up all those buttery juices. I always end up grabbing an extra piece.
Honey Glazed Carrots: Sweet, buttery Honey Glazed Carrots balance out the richness of the roast beautifully and add a nice pop of color to the plate.
Cheesy Bacon Green Beans: My Cheesy Bacon Green Beans are a family favorite with this recipe. The smoky bacon and gooey cheese go perfectly with the tender beef.
Over baked potatoes: This is one of my favorite ways to serve it. Load up fluffy Air Fryer Baked Potatoes with a generous scoop of the pot roast and drizzle a bit of the sauce on top. It’s hearty, filling, and perfect for family dinners. You could even take a note from my Sloppy Joe Baked Potatoes and add a little shredded cheese or sour cream for a fun twist.

Storage and Freezing

How should I store Slow Cooker Mississippi Pot Roast?

Keep leftovers in an airtight container in the fridge for up to 4 days. The flavors deepen as it sits.

Can I freeze Slow Cooker Mississippi Pot Roast?

Yes. Cool completely, then freeze in containers or bags for up to 3 months. Thaw overnight and reheat slowly on the stove or in the slow cooker.

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Fork pulling a piece of tender Mississippi Pot Roast from a plate of mashed potatoes with pepperoncini on top.

Tips & Tricks

Pick the right roast: Chuck roast is the way to go here. It has just enough marbling to stay juicy and tender after hours in the slow cooker. Leaner cuts like round roast tend to dry out.
Be patient with the lid: I know it’s tempting to peek, but every time you lift the lid, you lose heat and slow down the cooking. Let it work its magic undisturbed until it’s time to shred.
Go easy on salt: The seasoning mixes already bring plenty of flavor, so there’s no need to add more salt until you taste it at the end.
Add veggies for a full meal: Toss in chunks of carrots, onions, or baby potatoes if you want a one-pot dinner. They’ll soak up that delicious sauce while the roast cooks.
Plan for leftovers: The flavor gets even better after a night in the fridge. Use the extra beef in sandwiches, wraps, or even loaded Baked Potatoes for an easy second meal.

More Beefy Mains

Looking for more meal inspiration?

Browse my Slow Cooker Meals or check out my One Pot Dinners for more yummy ideas.

FAQ

Can I use a different cut of beef?
Yes, but chuck roast really gives you that fall-apart texture. Brisket or a round roast will work, though they might not turn out quite as tender.
Can I cook it faster on high?
You can, but it’s worth giving it time on low if you can. Slow cooking helps the meat break down and stay juicy.
Can I make this without butter?
The butter adds richness and flavor, but if you’re trying to lighten it up, you can leave it out.
Do I need to add any liquid?
Nope! The butter, seasonings, and natural juices from the beef create their own flavorful sauce as it cooks.
Can I prepare it ahead of time?
Definitely. Layer everything in your slow cooker insert the night before, cover it, and keep it in the fridge. In the morning, just set it in the cooker and turn it on.
Can I add vegetables?
Yes, and it’s a great way to make it a full meal. Carrots, onions, and potatoes hold up best to the long cooking time.
How do I make it less salty?
Choose low-sodium ranch and au jus mixes and use unsalted butter.
Can I make it spicy?
Add extra pepperoncini or more of their brine for a little heat. It gives the sauce more depth without overpowering the roast.
What should I serve it with?
It’s amazing with Garlic Mashed Potatoes or Rustic Bread to soak up the sauce, and I love adding Southern Broccoli Casserole on the side for extra comfort!